Matthew T. Colonnese, PhD
Principal Investigator | PhD Yale University
Dr. Colonnese established the Laboratory for Systems Neural Development at the George Washington University Medical School in Washington, D.C. in 2011. The group studies early brain activity using a multi-disciplinary approach including in vivo electrophysiology and network analysis of brain activity in the neonatal rodent. Dr. Colonnese' expertise includes in vivo electrophysiology and fMRI in developing rodents, analysis of EEG in preterm infants, and anatomical assays of synapse development and connectivity in sensory systems. Dr. Colonnese is an active scientist and lecturer, and continues to seek close relationships with clinicians to ensure the relevance of the laboratory's work to human health and development.
Dr. Murata studies how neuronal activity propagates in intact neonatal animals. Activity is crucial for normal circuit formation, but is usually assumed to be passively transmitted. Dr. Murata's work is revealing active mechanisms used by the developing brain to compensate for weak immature connections and ensure efficient information transfer, which facilitates proper wiring. His expertise includes molecular biology, in vivo electrophysiology and 2-photon imaging, optogenetics, mass spectroscopy-based proteomics, and synaptic biochemistry.
Marnie Phillips, PhD
PhD Massachusetts Institute of Technology
Dr. Phillips is a developmental neurobiologist interested in the extent to which external factors, like experience, can influence synaptic development of the brain. Her expertise includes ion channel electrophysiology, molecular cloning, synaptic analysis, viral mediated gene transfer, biochemistry, neuroanatomy and science writing. Dr. Phillips' work is helping to understand the degree to which sensory input is able to shape the neonatal brain, and is focused on development and funding of new projects, training, compliance, and problem solving.
Maria Pompeiano, MD PhD
MD PhD University of Pisa, Italy
Dr. Pompeiano is interested in the neurochemical basis of sleep-wake cycle development. Her research is identifying the neuromodulator systems important for early sleep and wake behaviors in developing animals. Her expertise includes over 20 years of experience in the biology of sleep and circadian rhythms, biochemistry, neuroanatomy and behavioral analysis.
Pouria Riyahi, MS
MS George Washington University
Mr. Riyahi is studying the effects of common neonatal insults on the normal development of activity in the cerebral cortex. He conducts in vivo experiments and applies his engineering background in signal processing to the analysis of electrocorticographic activity in the developing neonatal rodent.
He earned his Master's in Engineering from GWU and is pursuing a doctoral degree in Biomedical Science at GW under the mentorship of Dr. Colonnese.
Ruben Tikidzhi-Khamburyan, PhD
MS Physics Southern Federal University
PhD Computer Science/Neuroscience
Kogan Research Institute for Neurocybernetics, Russia,
Dr Tikidzhi-Khamburyan is a computational and theoretical neuroscientist interested in information processing in neural networks. He is creating detailed biophysical models of network development to understand the neuronal mechanisms of sensory perception and how early neuronal assemblies are formed.