December 7, 2016

Daily changes in the activity of developing mouse cortex until postnatal day (P)24.

October 1, 2013

The project, titled “Emergence of Visual Alertness in Cortical Networks,” is focused on understanding how activity and circuit properties change in the cerebral cortex between the fetal and postnatal periods to allow visual awareness at birth.

October 1, 2012

With support from Children's and a gift from Dr Jack and Shirley Kaplan to George Washington University, this study is using a rat model of Fragile X syndrome (FXS) to identify the earliest possible cortical activity deficits in Fragile X syndrome.  The results should inform development of pre-symptomatic EEG based diagnostics for autism in at-risk populations such as very pre-term infants. Identification of the network and synaptic mechanisms of the earliest deficits in cortical processing is important to identify new treatment targets that can be delivered at the appropriate ages....

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A cortico-thalamic 'booster' circuit amplifies and conditions weak sensory inputs to the fetal brain.

October 11, 2016

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